Psychology Reader

No Persistent Attenuation of Fear Memories in Humans: A Registered Replication of the Reactivation-Extinction Effect

Anastasia Chalkia, Natalie Schroyens, Lu Leng, and 4 others · 2020 · Cortex

Role
Replication · Critical reappraisal
Difficulty
Moderate
Full work length
14 pages
Type
Journal article

Access

  • DOI · Cortex ↗Publisher record. An accessible copy is linked below.
  • Public archive copy · PubMed Central ↗Public full-text archive copy. The final article is pp. 496–509; HTML has no fixed page breaks. The registered replication is distinct from the authors' separate verification report.

Psychology Reader links to legitimate sources and does not host article PDFs.

Reading focus

Syllabus: Why Does Learned Behavior Persist—and When Does It Change?

Compare the critical conditions, exclusions, outcome processing, and between-group inference with the original paper. Track what this direct replication tests and what lies outside its design.

A question to consider. Revise a claim about the original procedure in light of this result, stating both what is less secure and what remains unanswered.

Why this reading

A direct replication tests whether a consequential effect can be reproduced under a specified protocol. This study also shows why identifying the original inclusion criteria and making analysis decisions explicit are part of the substantive scientific question.

Before you read

The critical comparison is extinction ten minutes after a reminder versus extinction without that reminder. A registered report evaluates a proposed study before its results are known. Inclusion criteria determine whose data contribute to the estimate; preprocessing changes how physiological recordings become scores. Track the documented protocol amendments as well as the original preregistration.

Read for

  1. Identify what is directly replicated and what is outside the design. The study does not reproduce every condition, the original second experiment, or the one-year follow-up.
  2. Follow the path from recruitment to the analyzed sample and the revised criteria obtained from the original authors. Ask how exclusions affect precision and interpretation.
  3. Compare the planned between-group test of returning responses with separate within-group significance tests. Examine whether conclusions depend on the physiological scoring procedure.

Consider afterwards

  1. A replication finds no advantage for a ten-minute reminder. What claim about that protocol is weakened, and what broader claims about memory would require different experiments?

Editorial context

The study analyzed 124 participants after recruiting 246 and found no benefit of reactivation-extinction in its critical conditions. It challenges the robustness of that procedure's advantage; it does not establish that all reconsolidation interventions fail or that memories can never change. Its discussion addresses discrepancies in the original exclusion criteria and the 2018 addendum. Do not confuse this registered replication with the separate 2020 verification report and that report's 2021 corrigendum.